Etinosa Idemudia was born in Warri, Delta State, Nigeria to Sylvester and Patricia Idemudia. She had her primary and secondary education at Victory International School, Warri; Cambridge International School, Warri; and Igbinedion Education Centre, Oka, Benin City, Edo State. She proceeded to Covenant University, Ota, Ogun State, from where she holds a degree in Computer Engineering. She also holds a Diploma in Performing Arts from the Royal Art Academy, Lagos.

Preceding her incursion into the film industry, Idemudia worked as a Construction/Planning Engineer with an Engineering company. Idemudia gained wide recognition for her online comedy skits via instagram, and made her screen debut in a minor role in the 2016 film, ‘’A Little White Lie’’. Idemudia is notable for ‘’Losing Control’’ (TV Series, 2016), ‘’Adventures of Etinosa’’ (Web Series, 2016), ‘’How to Die in An African Home’’ (Web Series, 2016), ‘’Bradford Mansion’’ (2016), ‘’Ajuwaya’’ (2017), ‘’Alter Ego’’ (2017), ‘’Stormy Hearts’’ (2017), ‘’Mentally’’ (2017), ‘’Love in the Wrong Places’’ (2017), ‘’Corper Shun’’ (TV Series, 2018), ‘’The Chairman’’ (TV Series, 2018), ‘’Sunshine’’ (2018), and ‘’The Blindspot’’ (2018).

In 2018, Idemudia starred and made her debut as a film producer in ‘’The Washerman’’ (2018).